Pesquisa sobre: TOR SERINE-THREONINE KINASES 
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Descritor Inglês:   TOR Serine-Threonine Kinases 
Descritor Espanhol:   Serina-Treonina Quinasas TOR 
Descritor Português:   Serina-Treonina Quinases TOR 
Sinônimos Inglês:   mTOR Serine-Threonine Kinases
TOR Kinases  
Categoria:   D08.811.913.696.620.682.700.931
D12.776.476.925
Definição Inglês:   A serine threonine kinase that controls a wide range of growth-related cellular processes. The protein is referred to as the target of RAPAMYCIN due to the discovery that SIROLIMUS (commonly known as rapamycin) forms an inhibitory complex with TACROLIMUS BINDING PROTEIN 1A that blocks the action of its enzymatic activity. 
Nota Histórica Inglês:   2011 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   54051 
Identificador Único:   D058570 

Ocorrência na BVS:
 

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